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专利名称：Fluorescence observation apparatus and
fluorescence observation method
发明人：Yasushige Ishihara申请号：US12524804申请日：20080130公开号：US08547425B2公开日：20131001
专利附图：
摘要：The diagnosability of diseased parts is improved by precisely correctingfluorescence images without being affected by specular reflection and without beingaffected by thick blood vessels. Provided is a fluorescence observation apparatus that
includes a light source unit that radiates, onto an observation target site, illuminationlight that is in the wavelength band absorbed by a blood vessel, first excitation light thatincludes the wavelength band of the illumination light and generates autofluorescenceby exciting an autofluorescent substance in the blood vessel, and second excitation lightthat is in a different wavelength band from the first excitation light and generates agentfluorescence by exciting fluorescent dye that selectively stains normal tissue andabnormal tissue; an image-acquisition unit that obtains respective images by capturingreflected light, autofluorescence, and agent-fluorescence, obtained by radiating theillumination light, and the first and the second excitation light onto the same observationtarget site; and an image processing unit that extracts a blood-vessel image from theobtained reflected-light image, obtains a reference image by applying interpolation to anarea in the autofluorescence image corresponding to the extracted blood-vessel image,and corrects the agent-fluorescence image, obtained by the image-acquisition unit, basedon the obtained reference image.
申请人：Yasushige Ishihara
地址：Tokyo JP
国籍：JP
代理机构：Scully, Scott, Murphy & Presser, P.C.
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